relation: http://miis.maths.ox.ac.uk/miis/342/
title: Mathematical Models for Estimating the Risk of vCJD Transmission
creator: Anvari, V.
creator: Atapour, M.
creator: Bourouiba, L.
creator: Caudillo Mata, L. A.
creator: Collinson, S.
creator: Johnson, A.
creator: Madras, N.
creator: Miasnikof, P.
creator: Ramirez Ramirez, L. L.
creator: Sanchez-Bravo, I.
subject: Medical and pharmaceutical
description: We present two different simple models for vCJD transmission by blood transfusion. Both models indicate that transfusions alone are unlikely to cause more than a few infections, unless the number of primary cases increases.    To improve our models, future work should pursue data collection, empirical estimation of the model parameters, and examination of the underlying assumptions of our frameworks.    Further improvements could also include examining susceptibility to vCJD infection by age group and iatrogenic infections introduced through surgical instruments. Regarding the latter, it may be worthwhile to conduct experiments to quantify the transmission of prions from an infected surgical instrument after repeated sterilization procedures.
date: 2009
type: Study Group Report
type: NonPeerReviewed
format: application/pdf
language: en
identifier: http://miis.maths.ox.ac.uk/miis/342/1/vCJD.pdf
identifier:   Anvari, V. and Atapour, M. and Bourouiba, L. and Caudillo Mata, L. A. and Collinson, S. and Johnson, A. and Madras, N. and Miasnikof, P. and Ramirez Ramirez, L. L. and Sanchez-Bravo, I.  (2009) Mathematical Models for Estimating the Risk of vCJD Transmission.  [Study Group Report]