?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.relation=http%3A%2F%2Fmiis.maths.ox.ac.uk%2Fmiis%2F578%2F&rft.title=Interpreting+pharmaceutical+screening+test+results&rft.creator=D.%2C+Allwright&rft.subject=Medical+and+pharmaceutical&rft.description=In+the+pharmaceutical+industry%2C+compounds+are+tested+for+activity+against%0D%0Aa+disease+target.+In+a+High+Throughput+Assay+(HTA)%2C+each+compound+is%0D%0Atested+at+a+single+concentration.+In+an+IC50+test%2C+a+compound+is+tested%0D%0Aat+a+range+of+concentrations.+Sometimes+there+are+discrepancies+between%0D%0Athe+results+of+these+tests+and+the+Study+Group+was+asked+to+model+this.%0D%0ARather+than+assume+normally+distributed+errors+in+the+percentage+effect%2C%0D%0Athe+Study+Group+proposed+a+model+in+which+there+are+also+probabilities%0D%0Ap+and+q+of+a+test+erroneously+indicating+very+low+or+high+activity.+The%0D%0Aparameters+p+and+q+can+be+estimated+from+the+data%2C+and+then+can+be%0D%0Aused+in+the+design+of+testing+procedures.&rft.date=2011&rft.type=Study+Group+Report&rft.type=NonPeerReviewed&rft.format=application%2Fpdf&rft.language=en&rft.identifier=http%3A%2F%2Fmiis.maths.ox.ac.uk%2Fmiis%2F578%2F1%2F6.pdf&rft.identifier=++D.%2C+Allwright++(2011)+Interpreting+pharmaceutical+screening+test+results.++%5BStudy+Group+Report%5D+++++